You never fight cancer alone.

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Providence Cancer Institute of Orange County


Providence Cancer Institute of Orange County


World-class care in Orange County

At Providence, we see more than a cancer patient, we see the life you’re fighting for – and we have for nearly 100 years. That’s how long we’ve been providing world-class cancer care in Orange County.

Today, we’ve strengthened our commitment to you by integrating three nationally accredited cancer programs – Mission, St. Joseph and St. Jude.


Providence hospitals rated among the best in Orange County by U.S. News & World ReportRead more

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Premier Cancer Specialists

Expanded access to the brightest cancer experts across multiple cancer specialties in Orange County.

Patient Navigators

Cancer navigators who provide individual support, compassionate care and coordination every step of your cancer journey.

Advanced Technology

Access to the most advanced treatment options, including research, robotic surgery, genetic counseling and clinical trials.

Together, Providence Cancer Institute is the largest* integrated network of cancer care in Orange County, comprised of acclaimed physicians and specialists from Mission, St. Joseph and St. Jude cancer programs. We’re combining expertise of premier cancer specialists and patient navigators, as well as access to the most advanced technology and treatment options, including research, genetic counseling, precision medicine and clinical trials. From diagnosis to recovery, we see the life in you.

In addition, we offer extensive patient services and resources to support and guide you throughout this challenging time including online telehealth visits and second opinions.

All three of our Orange County hospitals have achieved the following accreditations to meet quality outcomes, perform continuous process improvement and standardization of care.

  • American College of Surgeons Commission on Cancer (CoC)
  • American College of Surgeons National Accreditation Program for Breast Centers (NAPBC)
  • American College of Radiology (ACR) Breast Imaging Center of Excellence
  • American College of Radiology CT Lung Screening Designation 

*Based on 2019 OSHPD cancer inpatient volumes and 2020 Trilliant outpatient claims.

At Providence, you are treated by a multidisciplinary team of specialists involved in every aspect of your cancer care – including gastroenterologists, radiologists, surgeons, pathologists, medical oncologists, and radiation oncologists - who collaborate across multiple locations to provide convenient, connected care close to your home or work. As a patient, you will have access to:

  • World-class treatment options, including access to advanced technologies and the latest clinical trials.
  • Comprehensive care across the care continuum: continuing and supportive care including home health, skilled nursing, hospice, supportive/palliative care, in-patient/out-patient rehabilitation, nutrition, counseling, social work, wellness and support groups.
  • One of our values is to ease the way of our patients. As part of this, our compassionate, cancer navigators support and coordinate your patient care journey every step of the way.
Our approach to cancer care at Providence is to treat the whole person and not just the illness. You are at the center of a team of specialists whose common goal is to cure, reduce recurrence, and provide access to integrative medicine and supportive care services designed to improve your overall quality of life.

All cancer patients have access to have their case reviewed at a tumor board, also known as multidisciplinary cancer conference. Tumor boards provide a collaborative, multidisciplinary approach to your cancer care, bringing together oncology, radiology, pathology, interventional radiology, genetics, and ancillary specialists to aid in treatment planning and improved care coordination.

One of the most important members of your Providence cancer team is a specially trained nurse navigator, who provides compassionate support and will keep you informed and help answer your questions so you can feel confident and in control of your care.

Genetic counseling is a process of receiving risk estimates, accurate understanding, management planning and empowerment for individuals and families who are concerned about their risks. It involves meeting with a licensed certified genetic counselor to review your personal and family history, to accurately interpret genetic test results, and to receive compassionate support. Genetic counselors provide personalized recommendations for screening, prevention, and risk reduction.

Genetic testing may help to rule out an inherited syndrome, provide an explanation for the occurrence of cancer or heart disease in you or in your family and predict elevated risk of developing additional disease. For individuals with a current cancer diagnosis, genetic testing can provide valuable information to your treating physicians in developing the best treatment plan.

Genetic testing and genetic counseling testing results can provide management recommendations to help treat and prevent disease and can be used to more accurately advise family members.

Yes, the vast majority of patients have insurance coverage for genetic testing and genetic counseling testing. Our patient account specialists verify coverage prior to the consultation. Individuals may also check eligibility and co-pay information by calling their insurance provider.

Genetic testing is billed by the third-party genetic testing laboratory directly. For most, the cost of genetic testing does not exceed $250. If the cost of the test is a barrier to you, your genetic counselor can discuss laboratory patient assistance programs and help you apply for them.

Inherited cancer syndromes are typically due to inherited “errors” or mutations within specific genes that normally function to prevent cancer. These inherited mutations cause a loss of normal gene function and increased risks of developing certain types of cancer. About 5-10% of individuals have a cancer caused by an inherited cancer syndrome.

Hereditary cardiac conditions are typically due to inherited “errors” or mutations within specific genes that disrupt the normal growth or function of the heart and other parts of the circulatory system. These inherited mutations can cause increased risk for progressive heart disease, especially at younger ages, or even cause dangerous cardiac events and lead to sudden death. About 1 in 250 individuals have inherited heart disease.

Our genetic counselors are qualified genetics professionals for all types of inherited risks, and are prepared to discuss the risk of developing other disorders of familial concern, including hematologic and adult neurologic syndromes. They can also help interpret direct-to-consumer tests and provide clarity on the implications of results for you and your family members. See Genetic Services for more information.

On average, genetic test results are available within 2-3 weeks.

  • Positive: A harmful mutation identified that may increase risk of developing certain conditions.
  • Negative: No mutation identified.
  • Variant of Unknown Significance: Genetic alteration identified, but our understanding of it is limited at this time.

Genetic testing is just one tool that genetic counselors use to provide you with the very best in personalized medicine that genetic testing alone cannot provide. Genetic counselors are genetic experts and remain up to date on the constantly changing field of genetics. They are trained to tailor, translate, and communicate complex genetic information into practical, accurate, and understandable decision-making information that you, your relatives, and your healthcare team can use to provide the best in individualized healthcare management. They help to insure the very best outcomes for you and your relatives.

Continued contact with genetic professionals is advised for many individuals who have undergone genetic counseling and/or genetic testing. Over time, new technologies are developed, new genes become available for testing, insurance criteria for testing may change making testing more accessible and management updates for mutation carriers become available. Additionally, family histories change over time making reassessment of the family history beneficial. We recommend having genetic counseling if you have significant family history and you previously had genetic testing without seeing a genetic counselor. In addition, we recommend contacting your genetic counselor every few years.

  • If you previously had genetic counseling but genetic testing was not done: If you underwent genetic counseling without genetic testing, you may benefit from meeting with a genetic counselor again. The criteria for genetic testing have expanded, insurance companies are much more likely to cover genetic testing, and the cost of genetic testing has decreased significantly. A genetic counselor can help you review your options, order the appropriate test, and review your results and their implications.
  • If you previously had genetic testing which identified a pathogenic mutation (positive results): With time, more information becomes available regarding specific hereditary cancer syndromes. If your previous genetic testing identified a mutation, it is important to keep in touch with your genetic counselor periodically to review the most up to date information regarding cancer risks and management guidelines and to make sure that your previous genetic testing was comprehensive.
  • If you previously had genetic testing which did not identify any mutations (negative results): With time, more hereditary cancer genes are being identified, comprehensive genetic testing is becoming more accessible, and genetic technologies are advancing. If your previous genetic testing was uninformative because it did not identify any mutations, updated genetic testing may be indicated.
  • If you previously had genetic testing which identified a variant of unknown or uncertain significance (VUS): With time, more information becomes available and variants of uncertain significance may get reclassified. A genetic counselor can review the current literature and data regarding your VUS, discuss what is known, what steps may be taken to reclassify it, and recommend further genetic testing if indicated.

Genetic testing for tumor molecular profiling (somatic) is different than genetic testing for inherited cancer risk (germline). Genetic testing of cancer tissue helps to characterize the tumor while genetic testing for inherited risk helps to estimate and reduce familial cancer risk. A genetic counselor can review tumor genetic test results in conjunction with your personal and family history to help you understand your results and your risk for an inherited cancer susceptibility syndrome.

Some DTC companies, such as 23andMe and Ancestry, offer "health" tests. These tests are not diagnostic and should not be used to make medical decisions. If you previously had DTC genetic testing and were told you had an increased risk of developing a certain condition, such as cancer, a genetic counselor can review these results with you and, if indicated, order diagnostic confirmatory testing.

In addition, DTC testing is very limited, looking at a few mutations while clinical genetic testing fully analyzes those and other relevant genes. Therefore, "normal" DTC testing results do not actually rule out hereditary cancer syndromes or other hereditary risks.

Federal and state laws provide protection against genetic discrimination. The Genetic Information Nondiscrimination Act (GINA) of 2008 is a federal law that protects people from health insurance eligibility discrimination including additional fees or costs and also protects from employment discrimination. GINA does not protect against all forms of genetic discrimination and does not specify protection from other insurance discrimination such as life, disability, and long-term care. Learn more about GINA. Our genetic counselors can discuss any concerns you may have regarding genetic testing and privacy.

For more information about the Cancer Genetics Program, please visit our website.

For any other questions or to schedule a genetic counseling appointment near you, contact us:

Providence Mission Hospital    
Phone: 949-573-9492                           
Fax: 949-364-4290
We are located at 27799 Medical Center Road, Mission Viejo, CA. within the Leonard Cancer Institute, on the 2nd Floor

Providence St. Joseph Hospital   
Phone: 714-734-6229                           
Fax: 714-734-6218
We are located at 1000 W. La Veta Ave, Orange, CA. within the Center for Cancer Prevention Treatment, on the 1st Floor

Providence St. Jude Medical Center   
Phone: 714-446-7181 x2019
Fax: 714-446-5666
We are located at 2151 N. Harbor Blvd, Fullerton, CA. within the Kathryn T. McCarty Breast Center, on the 2nd Floor (suite 2100)

We welcome your questions! Call 866-366-7183 for more information or complete the online form.

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Three Trusted Orange County Cancer Programs to Serve You

Together, we can deliver the best, most effective treatments for you. 

Cancers We Treat

At Providence, we have expertise in treating the following cancers.

  • Bile duct cancer
  • Bladder cancer
  • Breast cancer
  • Cervical cancer
  • Colon cancer
  • Endometrial cancer
  • Esophageal cancer
  • Gallbladder cancer
  • Prostate cancer
  • Rectal cancer
  • Skin cancer
  • Stomach cancer
  • Testicular cancer
  • Thyroid cancer
  • Vaginal cancer

Clinical Trials and Research

Clinical trials are research studies that involve people. Through clinical trials, doctors find new ways to improve treatments and the quality of life for people.

Clinical Trials Save Lives

Through clinical trials, doctors find new ways to improve treatments and the quality of life for people with disease.

Benefits and Risks

Clinical trials are experiments, so they may have risks as well as benefits. Risks depend on the treatment being studied and the health of people who participate.

Second Opinion

Patients can seek second opinions prior to initiating their treatment or during their cancer journey to see if they’re eligible for innovative new therapies – closer to home.

Doctor reassuring cancer patient
You Never Fight Cancer Alone

Read about our world-class compassionate cancer care in these Providence patient stories.

Clinical Excellence

Providence specialists devote their entire lives to curing cancer. Dedicated patient navigators, robust clinical trials, and world-class coordinated care push the boundaries of hope. 

Expert Tips and Cancer Resources

Learn more about Vicky Cook's courageous fight against breast cancer.
Providence Swedish Regional Cancer System’s Integrative Cancer Care Program offers patients an array of holistic medicine treatments designed to complement conventional medical cancer care.
In honor of Doctors' Day on March 30, we recognize the significant contributions of physicians and their commitment to providing the most advanced, highest quality care for our cancer patients.
Providence researchers receive awards for two studies of COVID-19’s impacts on colorectal cancer screenings and outcomes