Myelodysplasia and Myeloproliferative Disorder Care

When you’re a patient at Providence, we don’t just treat your illness – we treat you. We use the most advanced treatments to create a highly personalized care plan. We also support you and your loved ones with a full range of services throughout your entire journey. The result is effective, whole-person care for your body, mind and spirit.

Why Choose Us for Myelodysplasia and Myeloproliferative Disorder Care?

At Providence, we see the life in you. Together, let’s finish cancer – so you don’t have to miss any of life’s special moments.

No two patients, or their treatment plans, are alike. This is why, at Providence, we take a highly personalized approach to your blood and bone marrow disorder care. Our expert clinicians work with you to design a treatment plan that fits your personal needs. It’s an approach that combines leading-edge treatment with the compassionate care Providence is known for. Why? Because we know this results in the best outcomes.

As a patient, you’ll be supported throughout your entire care journey by our expert multidisciplinary care team of board-certified hematologists and radiation oncologists. It’s a team-based approach to myelodysplasia and myeloproliferative disorders. Your care team may also include nurse navigators, psychosocial specialists, nutritionists and other specialists. We also provide you and your family with a full range of support services well beyond conventional treatment, from genetic counseling and education to nutrition and pain management.

Learn more about the experts who make up our multidisciplinary cancer care teams.

Blood disease doesn’t discriminate, but access to great hematology care hasn’t always been the same for everyone. At Providence, we are deeply committed to making sure every patient we treat has access to the best care. We offer various location-specific services to help our patients receive equitable care, such as translation for non-English-speaking patients, telehealth and transportation assistance. We value, respect and support the racial, ethnic, religious, spiritual, gender, and sexual identities of each member of our diverse communities, and we welcome all patients, regardless of their ability to pay. We aim to make sure every patient is treated equally and with dignity – whoever you are, and wherever you’re at. 

As a patient at Providence, you have access to the largest community-based network in the United States. Being part of a collaborative network means that your local myelodysplasia and myeloproliferative disorder care team shares knowledge and experience with other world-class clinicians across 51 hospitals in seven states. The extent and power of our network is one of the reasons so many patients choose Providence for their hematology care each year.

Providence is well-known for offering options – and hope – to patients seeking the most advanced procedures and therapies to treat myelodysplasia and myeloproliferative disorders. Our network of experts and state-of-the-art labs offer the most advanced medical insights and treatments for our patients, such as molecular analysis of bone marrow and coagulation diagnostics. We look at the stage and the genetic makeup of your specific condition to determine which clinical trial could be most effective for you.

About Myelodysplasia and Myeloproliferative Disorders

Myelodysplasia and myeloproliferative disorders are diseases of the bone marrow and blood. In myelodysplastic diseases, there are fewer healthy white blood cells, red blood cells and platelets in the blood. In myeloproliferative diseases, too many stem cells develop, increasing the number of blood cells. The expert oncology teams at Providence use the most effective therapies to treat patients with every type of myelodysplasia and myeloproliferative disorder and their related conditions, including:

  • Essential thrombocytosis
  • Myelodysplasia
  • Polycythemia vera
  • Myelofibrosis

Testing and Diagnostics


Diagnostic tools help our clinicians determine which therapies will work best for each patient, based on many factors like the patient’s diagnosis and particular genetic profile. Your doctors will use multiple advanced diagnostic and prognostic tools to help design your individualized treatment plan, including:

Personalized Treatment for Myelodysplasia and Myeloproliferative Disorders

We take a team approach, because we know this offers the best success in managing and curing blood and bone marrow disorders. Your multidisciplinary team will work with you to design an individualized care plan, from diagnosis to post-treatment support. We offer many different therapies across our Providence locations. Depending on your condition, your personal care plan may include one or more of the following:

Systemic therapies travel through the bloodstream and may help replace missing nutrients, control blood cell destruction by the immune system or impact blood cell production rates. Sophisticated genetic analysis allows us to target therapies to specific DNA mutations that cause cancer cells to develop and grow. Systemic therapies include:

Autologous stem cell transplant is a procedure in which healthy blood-forming stem cells are taken from a patient's blood or bone marrow before being treated for cancer. After radiation or chemotherapy, the healthy cells are then returned to the patient to replace damaged cells. This procedure allows larger than usual doses of chemotherapy to be given, which often improves the cancer response to the therapy.

CAR T-cell therapy is a novel therapy that allows for a targeted immune system attack on specific cancer cells. This procedure removes specific immune cells (T cells) from the body and molecularly engineers them to attack specific cancer cells. These cells are then reinfused into the patient to kill the cancer cells.

Chemotherapy is the systemic use of cytotoxic chemicals to kill cancer cells. Today there are many medications (e.g., biological medications, immune treatments, targeted therapies) that do not fit the classic definition of chemotherapy yet are often included in this category.

Clinical trials represent research protocols that include the use of new drugs or drug combinations in a specific clinical situation.

Molecularly targeted therapy is the use of drugs that are molecularly targeted at a genetic mutation that has allowed the cancer to grow. This therapy enables personalized treatments for patients who carry certain genetic mutations or abnormalities.

Radiation therapy uses high-energy radiation from a source like X-rays or photons to kill cancer cells or shrink tumors. It may be part of a treatment plan that also includes systemic therapies and/or surgery. Radiation is sometimes used to help ease a patient’s pain or discomfort. Radiation therapies include:

Intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) are advanced types of radiation therapies. IMRT uses advanced technology to manipulate the radiation beams to conform to the shape of a tumor. VMAT is a subtype of IMRT in which the machine actively delivers radiation beams while moving in an arc around the patient.

This method of radiation delivery offers next-generation capabilities. The arc-based therapy provided via VMAT delivers high doses of radiation to more focused areas, reducing side effects and the overall treatment time for the patient. This treatment is particularly effective at treating several types of cancer while at the same time reducing toxicity and harm to vital organs.

This procedure is one of several new ways to deliver radiation therapy. It requires a sophisticated facility and equipment, along with highly specialized physicians. It is available at some Providence locations.

Stereotactic radiation (SABR/SBRT) is a group of treatments that includes stereotactic body radiation therapy (SBRT) and stereotactic ablative radiation (SABR) – both of which are adaptations of stereotactic radiosurgery (SRS) – for the treatment of targets in the body, but outside the brain. Similar to SRS, these techniques deliver very high doses of radiation using sophisticated motion management and patient immobilization techniques.

The number of radiation treatments is minimal and may range from one to five treatments delivered over one to two weeks.

This procedure is one of several new ways to deliver radiation therapy. It requires a sophisticated facility and equipment, along with highly specialized physicians. It is available at some Providence locations.

Surface-guided radiation therapy (SGRT/SIGRT) is an approach to radiation targeting that offers real-time beam guidance from face and body surface-recognition systems.

This treatment is particularly effective at treating several types of cancer while at the same time reducing toxicity and harm to vital organs, thus minimizing side effects.

This advanced procedure requires a sophisticated facility and equipment, along with highly specialized physicians. It is available at some Providence locations.

Three-dimensional conformal radiation therapy (3DCRT) is a radiation planning and treatment technique in which three-dimensional (3D) imaging enables improved targeting for radiation treatment. 3D planning with CT imaging makes radiation treatment much more conformal, or tailored to the target.

Find Care Close to You


We are proud to see our dedication to our patients recognized by the most well-respected programs and institutions in the United States. Several of our Providence locations have achieved the following accreditations:

Meet the Team

At Providence, you'll have access to a vast network of dedicated and compassionate providers who offer personalized care by focusing on treatment, prevention and health education.