Learn more about histotripsy and find out if you’re a candidate.

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Histotripsy at Providence Mission Hospital Mission Viejo

In March 2024, Providence Mission Hospital became the first hospital in California to provide histotripsy, a new treatment option for liver tumors. This FDA-approved sonic beam therapy has minimal side effects, and patients have little-to-no down time after the procedure. This groundbreaking treatment provides hope to our liver cancer patients who are not candidates for surgery or have tried other forms of treatment such as chemotherapy or radiation without success.

2253.2 miles away
949-365-2181

Histotripsy at Providence Mission Hospital Mission Viejo

In March 2024, Providence Mission Hospital became the first hospital in California to provide histotripsy, a new treatment option for liver tumors. This FDA-approved sonic beam therapy has minimal side effects, and patients have little-to-no down time after the procedure. This groundbreaking treatment provides hope to our liver cancer patients who are not candidates for surgery or have tried other forms of treatment such as chemotherapy or radiation without success.

2253.2 miles away

About Histotripsy

Mission Hospital is the first in California and among a select few in the world to offer histotripsy, a revolutionary, noninvasive treatment for malignant and benign liver tumors. The procedure works by using high-energy ultrasound waves that convert to sonic beams and destroy liver tumors without a single incision.

Benefits

Because the innovative histotripsy procedure is noninvasive, it minimizes the risk of infection, bleeding and other complications. Histotripsy can be used to effectively treat liver tumors in patients who are not candidates for open surgery or have been told their liver tumor is inoperable. The procedure is compatible with chemotherapy and/or radiation therapy and can also be used to treat metastatic cancer that has spread to the liver.

What to expect

During the histotripsy procedure, targeted ultrasound waves form bubble clouds that implode and collapse rapidly, destroying only tumor cells. After tumors are liquefied by the sonic beam, only tiny molecules remain in the body. These microscopic fragments are too small to allow the cancer to spread and regrow.

The robotic-assisted histotripsy procedure is performed and controlled by our specially trained interventional radiologists using sophisticated imaging technology.

Patients receive general anesthesia to minimize movement during the procedure, but it is not painful. Patients typically go home the same day they have the procedure.

Our approach

For more than 50 years, Mission Hospital has been delivering comprehensive and innovative health care services in Southern California.

We are dedicated to providing state-of-the-art cancer care with expertise, skill and compassion. As a leader in noninvasive tumor treatment, we offer patients a specialized and innovative approach to managing liver tumors.

Why Choose Us for Histotripsy?

As the first hospital in the state of California to perform histotripsy, we are a destination for patients seeking noninvasive treatment for malignant and benign liver tumors.

Providence Mission Hospital offers effective options to patients seeking the most advanced therapies for liver cancer. We are pioneering its use in the region. Mission Hospital began offering the histotripsy procedure soon after the treatment was approved by the FDA in late 2023, making us the first site in California. We are one of the world’s highest volume centers, which means a more experienced, precise procedure and a better outcome for you. Our leadership in innovation helps us provide better care – and a better life – for you and your loved ones.

Your oncologist gets to know you personally to create a care plan tailored to your specific cancer type, tumor and other factors. And your care doesn’t end after your procedure. You'll continue to have a relationship with your oncologist for continued monitoring and expert care as needed. This patient-centered approach is why patients have trusted Mission Hospital with their cancer care for over 60 years. 

As our patient, you and your loved ones are supported by an entire care team throughout your treatment journey. Our board-certified interventional radiologists will perform your histotripsy procedure, bringing trusted experience to your treatment. They work closely with a care team of specialized clinicians who are trained in using image-guided, advanced ultrasound technology to ensure precise targeting of tumors.

Breakthrough Cancer Therapy

See how this new medical device effectively targets cancerous liver tumors.

How Our Providers Are Impacting Patients

Because histotripsy is noninvasive it opens up treatment for liver tumors to a host of patients who otherwise wouldn’t be candidates for surgery. There’s no incision, no needles, no bleeding. There’s no other treatment like this.

Kevin Burns, MD | Interventional Radiologist, Providence Mission Hospital

Meet the Team

At Providence, you'll have access to a vast network of dedicated and compassionate providers who offer personalized care by focusing on treatment, prevention and health education.

Doctor sitting with patient
The Power of Our Network

Part of the Providence Cancer Institute of Orange County

From diagnosis to recovery and beyond, we’re with our patients every step of the way. We’ve integrated three nationally accredited cancer programs – Mission, St. Joseph and St. Jude – to provide you with:

  • Board-certified cancer specialists who collaborate across locations to provide convenient, connected care close to your home or work.
  • Innovative screening that can detect more than 50 types of cancer through a single blood draw.
  • Patient navigators for each cancer type who will help you manage your treatment and find the resources you need.

Learn More About the Providence Cancer Institute of Orange County